A destitute artist, sex worker, and radical feminist writer drops out of grad school in 1960s New York and drifts into the orbit of Andy Warhol's Factory as the author of the anti-male SCUM Manifesto. As her paranoia, brilliance, and rage compound, the story arcs toward the June 1968 attempted assassination that would briefly make her infamous, in a portrait of outsiderdom, ideology, the limits of the Factory, and rebellion without an outlet.